Reintroduced with great fanfare as a 2005 model (and overdue for a refresh), the venerable Chrysler 300 continues to roll in style as the marquee’s flagship. Available with a range of engines and in both rear-wheel and all-wheel drive, the domestically-available Chrysler 300’s best gas mileage results come with the 2.7-liter V6 engine producing highway ratings in the mid-twenties in rear-wheel-drive form. On the flip side of the coin, the thirsty Hemi-powered 300/SRT-8’s gas mileage earns it an official status of gas guzzler (complete with federal tax).

A highly fuel-efficient version of the 300 is available in Europe, equipped with a Mercedes-Benz 3.0-liter turbodiesel V6 engine. While Jeep sells the Grand Cherokee CRD with the same engine here in the States, Chrysler has never sold a diesel-engined Chrysler 300 domestically. This is truly unfortunate, as the turbo-diesel 300 is capable of highway mileage in the mid-thirties, with an abundance of torque.
Chrysler 300 Gas Mileage: 1999-2009
| Year | Manf. | Model | Engine | Disp. | Fuel | Trans. | City | Hwy |
| 2009 | CHRYSLER | 300 AWD | 8 cylinder | 5.7 liter | R | (L5) Auto | 16 | 23 |
| 2009 | CHRYSLER | 300 AWD | 6 cylinder | 3.5 liter | R | (L5) Auto | 17 | 23 |
| 2009 | CHRYSLER | 300 | 6 cylinder | 2.7 liter | R | (L4) Auto | 18 | 26 |
| 2009 | CHRYSLER | 300/SRT-8 | 8 cylinder | 6.1 liter | R | (L5) Auto | 13 | 19 |
| 2009 | CHRYSLER | 300 | 6 cylinder | 3.5 liter | R | (L4) Auto | 17 | 25 |
| 2009 | CHRYSLER | 300 | 8 cylinder | 5.7 liter | R | (L5) Auto | 16 | 25 |
| 2008 | CHRYSLER | 300 AWD | 8 cylinder | 5.7 liter | R | (L5) Auto | 15 | 22 |
| 2008 | CHRYSLER | 300 AWD | 6 cylinder | 3.5 liter | R | (L5) Auto | 15 | 22 |
| 2008 | CHRYSLER | 300 | 8 cylinder | 5.7 liter | R | (L5) Auto | 15 | 23 |
| 2008 | CHRYSLER | 300 | 6 cylinder | 3.5 liter | R | (L5) Auto | 17 | 24 |
| 2008 | CHRYSLER | 300 | 6 cylinder | 3.5 liter | R | (L4) Auto | 17 | 24 |
| 2008 | CHRYSLER | 300 | 6 cylinder | 2.7 liter | R | (L4) Auto | 18 | 26 |
| 2007 | CHRYSLER | 300 AWD | 6 cylinder | 3.5 liter | R | (L5) Auto | 17 | 24 |
| 2007 | CHRYSLER | 300 AWD | 8 cylinder | 5.7 liter | R | (L5) Auto | 17 | 24 |
| 2007 | CHRYSLER | 300/SRT-8 | 8 cylinder | 6.1 liter | P | (L5) Auto | 14 | 20 |
| 2007 | CHRYSLER | 300 | 6 cylinder | 2.7 liter | R | (L4) Auto | 21 | 28 |
| 2007 | CHRYSLER | 300 | 6 cylinder | 3.5 liter | R | (L5) Auto | 19 | 27 |
| 2007 | CHRYSLER | 300 | 8 cylinder | 5.7 liter | R | (L5) Auto | 17 | 25 |
| 2006 | CHRYSLER | 300C AWD | 6 cylinder | 3.5 liter | R | (L5) Auto | 17 | 24 |
| 2006 | CHRYSLER | 300C AWD | 8 cylinder | 5.7 liter | R | (L5) Auto | 17 | 24 |
| 2006 | CHRYSLER | 300C | 6 cylinder | 2.7 liter | R | (L4) Auto | 21 | 28 |
| 2006 | CHRYSLER | 300C | 6 cylinder | 3.5 liter | R | (L4) Auto | 19 | 27 |
| 2006 | CHRYSLER | 300C | 6 cylinder | 3.5 liter | R | (L5) Auto | 19 | 27 |
| 2006 | CHRYSLER | 300C | 8 cylinder | 5.7 liter | R | (L5) Auto | 17 | 25 |
| 2006 | CHRYSLER | 300C/SRT-8 | 8 cylinder | 6.1 liter | P | (L5) Auto | 14 | 20 |
| 2005 | CHRYSLER | 300C AWD | 8 cylinder | 5.7 liter | R | (L5) Auto | 17 | 24 |
| 2005 | CHRYSLER | 300C AWD | 6 cylinder | 3.5 liter | R | (L5) Auto | 17 | 24 |
| 2005 | CHRYSLER | 300C | 6 cylinder | 2.7 liter | R | (L4) Auto | 21 | 28 |
| 2005 | CHRYSLER | 300C | 6 cylinder | 3.5 liter | R | (L4) Auto | 19 | 27 |
| 2005 | CHRYSLER | 300C | 8 cylinder | 5.7 liter | R | (L5) Auto | 17 | 25 |
| 2004 | CHRYSLER | 300 M | 6 cylinder | 3.5 liter | R | (L4) Auto | 18 | 27 |
| 2003 | CHRYSLER | 300 M | 6 cylinder | 3.5 liter | R | (S4) Auto | 18 | 27 |
| 2002 | CHRYSLER | 300 M | 6 cylinder | 3.5 liter | R | (S4) Auto | 18 | 26 |
| 2001 | CHRYSLER | 300M | 6 cylinder | 3.5 liter | R | (S4) Auto | 18 | 26 |
| 2000 | CHRYSLER | 300 M | 6 cylinder | 3.5 liter | R | (L4) Auto | 18 | 26 |
| 1999 | CHRYSLER | 300 M | 6 cylinder | 3.5 liter | R | (L4) Auto | 18 | 27 |
| 1980 | CHRYSLER | CORDOBA/300 | 8 cylinder | liter | 7 | (A3) Auto | 13 | 18 |
| 1980 | CHRYSLER | CORDOBA/300 | 6 cylinder | liter | 7 | (A3) Auto | 17 | 25 |
| 1980 | CHRYSLER | CORDOBA/300 | 8 cylinder | liter | 7 | (A3) Auto | 15 | 23 |
| 1980 | CHRYSLER | CORDOBA/300 | 8 cylinder | liter | 6 | (A3) Auto | 15 | 22 |
| 1980 | CHRYSLER | CORDOBA/300 | 8 cylinder | liter | 7 | (A3) Auto | 16 | 24 |
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